Trending

Stories

Hydroxychloroquine-azithromycin Combo May Be Potentially Lethal

Tidio Live Chat Software - Add Tidio live chat software to your website in minutes. Contact visitors and turn them into happy customers. Enhance their experience and boost your sales. Get it for Free

WP Rocket - WordPress Caching Plugin

Must Read

Hydroxychloroquine and azithromycin, which have been proposed for the treatment of COVID-19 patients, are a potentially lethal combination and may have a serious impact on the cardiovascular system, according to a study.

The researchers, including those from Vanderbilt University and Stanford University in the US, carried out an observational, retrospective meta-analysis of a WHO database encompassing over 21 million adverse event case reports.

Also Read

The reports span all medication classes from over 130 countries between November 14, 1967, and March 1, 2020 — mainly before the COVID-19 pandemic.

The study, published in the journal Circulation, compared cardiovascular adverse-drug reactions (CV-ADRs) in patients who received hydroxychloroquine, azithromycin, or the combination of both medications with all other cardiovascular medications in the database.

Elegant Themes - The most popular WordPress theme in the world and the ultimate WordPress Page Builder. Get a 30-day money-back guarantee. Get it for Free

Hydroxychloroquine and azithromycin, alone or in combination, have been proposed for the treatment of COVID-19 patients, the researchers said.

They explained that reports of potentially lethal acute cardiac arrhythmogenic effects — promoting irregular heart rhythms — have been described mainly with azithromycin but also with hydroxychloroquine.

Their combination yielded an even stronger signal, the scientists said.

Hydroxychloroquine was also associated with potentially lethal heart failure when exposure was prolonged over several months, according to the researchers.

From the more than 21 million case reports of adverse drug reactions, the researchers extracted case reports for hydroxychloroquine and azithromycin, alone or in combination.

They found that 76,822 adverse event reports were associated with hydroxychloroquine alone, and in 28.4 percent of those cases (21,808), the drug was suspected to be associated with the adverse event.

The study found that 89,692 adverse event reports were associated with azithromycin alone, and in 60.8 per cent of those cases (54,533), the medication was suspected to be associated with the adverse events.

The researchers said 607 adverse event reports were associated with the combination of both medications.

Hydroxychloroquine was significantly associated with the development of conduction disorders, and heart failure, they said.

On Monday, the World Health Organization also suspended testing hydroxychloroquine in COVID-19 patients due to safety concerns, WHO Director-General Tedros Adhanom Ghebreyesus said.

iThemes WordPress Hosting

Stay updated

Subscribe to our newsletter and never miss an update on the latest tech, gaming, startup, how to guide, deals and more.

Latest

Stories

- Advertisement -
- Advertisement -

Latest

Grow Your Business

Place your brand in front of tech-savvy audience. Partner with us to build brand awareness, increase website traffic, generate qualified leads, and grow your business.

- Advertisement -

Grow Your Business

Get these business solutions, tools and services to help your business grow.
Elementor

Elementor -Join 5,000,000+ Professionals Who Build Better Sites With Elementor. Build your website with 100% visual design that loads faster and speeds up the process of building them.

WP Rocket

WP Rocket - Speed up your website with the most powerful caching plugin in the world. The website speed increase means better SEO ranking, user experience, and conversation. It’s a fact that Google loves a fast site.

Kinsta

Kinsta - If you are looking for WordPress managed hosting, Kinsta is in the leading front. Kinsta provides WordPress hosting for a small or large business that helps take care of all your needs regarding your website with cutting-edge technology.

OptinMonster

OptinMonster - Instantly boost leads and grow revenue with the #1 most powerful conversion optimization toolkit in the world. 700,000+ websites are using OptinMonster to turn their traffic into leads, subscribers, and sales.

Related

- Advertisement -
- Advertisement -
ChatGPT Reaches 100 Million Users in Two Months Microsoft’s Teams Get OpenAI-Based Features WhatsApp New Feature that Allows Users to Create Calling Shortcuts Instagram Working On Twitter-like Paid Verification Feature OnePlus Ace 2 Specs Exposed Online Realme GT Neo 5 Full Specs Revealed  Samsung Galaxy S23 Ultra: The New Android King Twitter To End Free API February 9 MLS Season Pass Now Available On Apple TV App Tesla To Increase Giga Shanghai EV Production to 20,000 Weekly 
OpenAI Releases Tool To Detect AI-generated Text Tesla Records Double Net Profit in 2022 India to Produce Upcoming iPhones: Trade Minister Japanese Professor Developed A Power Semiconductor made of Diamond Google Releases New Product for India’s Merchants Indian EV Startup Unveil Two AutoBalancing Electric Scooters OPPO Find X6 Pro Images Render via Weibo Sony Develops New Tech to Reduce Noise of Image Sensors