Trending

Stories

Health Experts Are Not Unanimous About Certain Drugs for COVID-19

Tidio Live Chat Software - Add Tidio live chat software to your website in minutes. Contact visitors and turn them into happy customers. Enhance their experience and boost your sales. Get it for Free

WP Rocket - WordPress Caching Plugin

Must Read

Health officials worldwide are clashing over the use of certain drugs for COVID-19, leading to different treatment options for patients depending on where they live.

On Friday, a World Health Organisation guidelines panel advised against using the antiviral remdesivir for hospitalized patients, saying there’s no evidence it improves survival or avoids the need for breathing machines.

Also Read

But in the US and many other countries, the drug has been the standard of care since a major, government-led study found other benefits. It shortened recovery time for hospitalized patients by five days on average, from 15 days to 10.

Within the US, a federal guidelines panel and some leading medical groups have not endorsed two other therapies the Food and Drug Administration authorized for emergency use — Eli Lilly’s experimental antibody drug and convalescent plasma, the blood of COVID-19 survivors.

Elegant Themes - The most popular WordPress theme in the world and the ultimate WordPress Page Builder. Get a 30-day money-back guarantee. Get it for Free

The groups say there isn’t enough evidence to recommend for or against them.

Doctors also remain uncertain about when and when not to use the only drugs known to improve survival for the sickest COVID-19 patients: dexamethasone or similar steroids.

And things got murkier with Thursday’s news that the anti-inflammatory drug tocilizumab may help.

Like the key WHO study on remdesivir, the preliminary results on tocilizumab have not yet been published or fully reviewed by independent scientists, leaving doctors unclear about what to do.

It’s a genuine quandary, said the University of Pittsburgh’s Dr. Derek Angus, involved in a study testing many of these treatments. We need to see the details. Dr. Rochelle Walensky, infectious disease chief at Massachusetts General Hospital, agreed.

It’s tough to practice medicine by press release; she said on a podcast on Thursday with a medical journal editor- Until the National Institutes of Health’s guidelines endorse a treatment, I’m really reluctant … to call that standard of care. Angus said there are legitimate questions about all of the drug studies.

It’s not unusual for professional guidelines to disagree with each other. It’s just that it’s all under the microscope with COVID-19, he said.

The rift over remdesivir, sold as Veklury, by Gilead Sciences Inc., is the most serious.

The WHO guidelines stress that the drug does not save lives, based heavily on a WHO-sponsored study that was larger but much less rigorous than the US-led one that found it had other benefits.

The drug is given through an IV for around five days, and its high cost and lack of meaningful effect on mortality make it a poor choice, the WHO panel concluded.

Gilead charges USD 3,120 for a typical treatment course for patients with private insurance and USD 2,340 for people covered by government health programs in the U.S. and other developed countries. In poor or middle-income countries, much cheaper versions are sold by generic makers.

This week, the Institute for Clinical and Economic Review, a nonprofit group that analyzes drug prices, said remdesivir should be priced around USD 2,470 for hospitalized patients with moderate to severe disease because of the cost savings from fewer days of care. However, it’s worth only USD 70 for patients hospitalized with milder disease, the group concluded.

Price also may be driving lower demand. In October, US health officials said that hospitals had bought only about one-third of the doses of remdesivir that they were offered over the previous few months, when the drug was in short supply.

Between July and September, 500,000 treatment courses were made available to state and local health departments, but only about 161,000 were bought.

In a separate development, the FDA on Thursday gave emergency authorization to use another anti-inflammatory drug, baricitinib, to be used with remdesivir. In one study, adding baricitinib shaved an additional day off the average time to recovery for severely ill hospitalized patients.

Lilly sells baricitinib now as Olumiant to treat rheumatoid arthritis, the less common form of arthritis that occurs when a mistaken or overreacting immune system attacks joints, causing inflammation. An overactive immune system also can lead to serious problems in coronavirus patients.

iThemes WordPress Hosting

Stay updated

Subscribe to our newsletter and never miss an update on the latest tech, gaming, startup, how to guide, deals and more.

Latest

Stories

- Advertisement -
- Advertisement -

Latest

Grow Your Business

Place your brand in front of tech-savvy audience. Partner with us to build brand awareness, increase website traffic, generate qualified leads, and grow your business.

- Advertisement -

Grow Your Business

Get these business solutions, tools and services to help your business grow.
Elementor

Elementor -Join 5,000,000+ Professionals Who Build Better Sites With Elementor. Build your website with 100% visual design that loads faster and speeds up the process of building them.

WP Rocket

WP Rocket - Speed up your website with the most powerful caching plugin in the world. The website speed increase means better SEO ranking, user experience, and conversation. It’s a fact that Google loves a fast site.

Kinsta

Kinsta - If you are looking for WordPress managed hosting, Kinsta is in the leading front. Kinsta provides WordPress hosting for a small or large business that helps take care of all your needs regarding your website with cutting-edge technology.

OptinMonster

OptinMonster - Instantly boost leads and grow revenue with the #1 most powerful conversion optimization toolkit in the world. 700,000+ websites are using OptinMonster to turn their traffic into leads, subscribers, and sales.

Related

- Advertisement -
- Advertisement -
DJI Mini SE 2 Will Make its Debut On Feb 9 Motorola Launched Mote E13 Smartphone in India Google Pixel 4 and 4 XL Get Last Update WhatsApp Introduces 5 New Features For Status Updates OnePlus First-ever Tablet Launching in India Today ChatGPT Reaches 100 Million Users in Two Months Microsoft’s Teams Get OpenAI-Based Features WhatsApp New Feature that Allows Users to Create Calling Shortcuts Instagram Working On Twitter-like Paid Verification Feature OnePlus Ace 2 Specs Exposed Online
DJI Mini SE 2 Will Make its Debut On Feb 9 Motorola Launched Mote E13 Smartphone in India Google Pixel 4 and 4 XL Get Last Update WhatsApp Introduces 5 New Features For Status Updates OnePlus First-ever Tablet Launching in India Today ChatGPT Reaches 100 Million Users in Two Months Microsoft’s Teams Get OpenAI-Based Features WhatsApp New Feature that Allows Users to Create Calling Shortcuts