Trending

Stories

WHO to Restart Clinical COVID Drug Trial Aimed to Dampen Inflammation

Tidio Live Chat Software - Add Tidio live chat software to your website in minutes. Contact visitors and turn them into happy customers. Enhance their experience and boost your sales. Get it for Free

WP Rocket - WordPress Caching Plugin

Must Read

The World Health Organization (WHO) is set to restart an international clinical trial of three existing drugs that can save the lives of people hospitalized with Covid-19. This time the trial is aimed to dampen inflammation, an approach that has already shown promise, Nature reported.

The clinical trial, named Solidarity, was first announced on March 18 by WHO director-general Tedros Adhanom Ghebreyesus.

Also Read

The latest trial will test three drugs that dampen inflammation — Infliximab, Imatinib and Artesunate.

All three drugs were carefully chosen on the basis of the promise they showed in smaller clinical trials and widespread availability, John-Arne Rottingen, scientific director of the Norwegian Institute of Public Health, was quoted as saying.

Elegant Themes - The most popular WordPress theme in the world and the ultimate WordPress Page Builder. Get a 30-day money-back guarantee. Get it for Free

“You need at least promising signals that some of them will work. And we need to study drugs that we can deliver in a broad group of countries,” added Rottingen, who is also the chair of the Solidarity trial’s international steering committee.

The drug Infliximab is used to treat autoimmune conditions, including Crohn’s disease and rheumatoid arthritis. It blocks a protein called tumor necrosis factor-alpha (TNF-I), which is released by immune cells called macrophages and promotes inflammation.

The second in the trial is Imatinib, a cancer drug. Researchers hope that it will target both the Coronavirus and inflammation, blocking viral infiltration of human cells and reducing the activity of pro-inflammatory proteins called cytokines. And the third drug to be tested is Artesunate – an anti-malaria drug with potential anti-inflammatory effects.

Each of these drugs will be given alongside standard care, Rottingen said.

However, researchers must be careful that all these drugs do not suppress immune responses so much that people become vulnerable to other infections, said Djillali Annane, an intensive-care physician at the University of Versailles in Saint-Quentin-en-Yvelines, France.

The first Solidarity trial aimed to compare the effectiveness of four drugs and drug combinations – Remdesivir, interferon, the malaria drug hydroxychloroquine, and a combination of HIV drugs called lopinavir and ritonavir – in treating Covid-19.

By October, the trial had enrolled more than 11,000 participants hospitalized with Covid-19 in 30 countries. But the researcher found that none of the four drugs saved lives or shortened hospital stays.

iThemes WordPress Hosting

Stay updated

Subscribe to our newsletter and never miss an update on the latest tech, gaming, startup, how to guide, deals and more.

Latest

Stories

- Advertisement -
- Advertisement -

Latest

Grow Your Business

Place your brand in front of tech-savvy audience. Partner with us to build brand awareness, increase website traffic, generate qualified leads, and grow your business.

- Advertisement -

Grow Your Business

Get these business solutions, tools and services to help your business grow.
Elementor

Elementor -Join 5,000,000+ Professionals Who Build Better Sites With Elementor. Build your website with 100% visual design that loads faster and speeds up the process of building them.

WP Rocket

WP Rocket - Speed up your website with the most powerful caching plugin in the world. The website speed increase means better SEO ranking, user experience, and conversation. It’s a fact that Google loves a fast site.

Kinsta

Kinsta - If you are looking for WordPress managed hosting, Kinsta is in the leading front. Kinsta provides WordPress hosting for a small or large business that helps take care of all your needs regarding your website with cutting-edge technology.

OptinMonster

OptinMonster - Instantly boost leads and grow revenue with the #1 most powerful conversion optimization toolkit in the world. 700,000+ websites are using OptinMonster to turn their traffic into leads, subscribers, and sales.

Related

- Advertisement -
- Advertisement -
India to Produce Upcoming iPhones: Trade Minister Japanese Professor Developed A Power Semiconductor made of Diamond Google Releases New Product for India’s Merchants Indian EV Startup Unveil Two AutoBalancing Electric Scooters OPPO Find X6 Pro Images Render via Weibo Sony Develops New Tech to Reduce Noise of Image Sensors Tesla’s S & Y Models Earn Best-in-Class Cars of 2022 India Approved $320m to Promote Homegrown Payments Network Twitter Roll Out TikTok-like ‘For You’ Timeline on iOS Nothing Phone Enters US with Beta Membership Program
Finally! Apple’s VR Headset Coming this Spring Harvard Scientists Develop New Cell Therapy to Kill, and Prevent Brain Cancer HTC Vive XR Elite VR/AR Headset Now Selling for $1099 Realme 10 Launched in India with Helio G99 Gaming Chipset Twitter Data Breach Revealing User’s Private Information Instagram New Feature to Create Albums With Friend Redmi Note12 Pro Plus Launched in India POCO C50 Launched in India